Vasopressin 

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GENERIC NAME: VASOPRESSIN

Brand Name:

CLASS: Pituitary (antidiuretic) hormone Mechanism of Action:

Causes vasoconstriction (pressor effect) of peripheral, cerebral, pulmonary, and coronary vessels

Indications and Field Use:

Adult shock-refractory ventricular fibrillation/pulseless ventricular tachycardia

Contraindications:

Responsive patient with coronary artery disease

• Hypertension Adverse Reactions:

• Can increase peripheral vascular resistance and provoke cardiac ischemia and angina pectoris

• Abdominal distress
• Nausea and vomiting
• Tremors
• Tissue necrosis if extravasation occurs

NOTES ON ADMINISTRATION Incompatibilities/Drug Interactions:

None in the emergency setting

Adult Dosage:

For ventricular fibrillation/pulseless ventricular tachycardia: 40 U, one time only prior to administration of epinephrine

Routes of Administration:

IV, IO, ET 

© Matt Dillard 2012