Furosemide Lasix

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GENERIC NAME: FUROSEMIDE

BRAND NAME: Lasix CLASS: Loop diuretic

Mechanism of Action:

Pharmacologic: Inhibits electrolyte reabsorption in the ascending Loop of Henle. Promotes excretion of sodium, potassium, chloride. Vasodilation increases venous capacitance and decreases afterload. Clinical: Diuresis

Indications and Field Use:

Pulmonary edema; congestive heart failure

Contraindications:

Anuria (relative) Hypovolemia (relative) Hypotension (relative) Hypersensitivity

Adverse Reactions:

May exacerbate hypovolemia Hyperglycemia (due to hemoconcentration) Hypokalemia May decrease the response to pressors

NOTES ON ADMINISTRATION Incompatibilities/Drug Interactions: Increased effects with other antihypertensives

Adult Dosage:

0.5 to 1.0 mg/kg IVP to maximum dose of 40 mg CHF/Pulmonary Edema: 20-40 mg IV over 1-2 minutes

Pediatric Dosage:

1 mg/kg IV over 1-2 minutes

Routes of Administration:

Slow IV push each 40 mg over 1-2 minutes

Onset of Action:

5 minutes (vasodilation)

Peak Effects:

20-60 minutes (diuresis) Duration of Action:

Variable

Dosage Forms/Packaging:

20 mg/2 mL ampule, vial, syringe 40 mg/4 mL ampule, vial, syringe 100 mg/10 mL ampule, vial, syringe

Arizona Drug Box Supply:

PARAMEDIC: 100 mg

Special Notes:

> Ototoxicity and resulting deafness can occur.

> Since furosemide is a sulfonamide derivative, it may induce allergic reactions in patients with sensitivity to sulfonamides (sulfa drugs). 

© Matt Dillard 2012